A biopsy is the removal of tissue from any part of the body in order to examine it for disease. Some biopsies may remove a small tissue sample with a needle while others may surgically remove a suspicious nodule or lump. The type of procedure used to perform a biopsy will depend on the location of the tissue that needs to be examined.
Biopsies may be performed using imaging guidance—such as ultrasound, x-ray, computed tomography (CT) or magnetic resonance imaging (MRI)—to determine exactly where to place a needle through the skin to the area of the abnormality. Biopsies are most often done to look for cancer.
A biopsy might be recommended whenever:
- A mammogram shows a lump or mass, indicating the possibility of breast cancer.
- A mole on the skin has changed shape recently and melanoma is possible.
- A person has chronic hepatitis and it’s important to know if cirrhosis is present.